Promise of Cytogenetics in Tackling the Most Intractable Problems in Cancer Diagnosis, Therapy & Treatment to Drive the Global Molecular Cytogenetics Market

Epidemic spread of cancer, high patient unresponsiveness to conventional therapy standards, and the promise of cytogenetics in tackling the toughest challenges in battling cancer are poised to drive the global market for Molecular Cytogenetics to reach US$2.3 billion by 2022.  

Molecular Cytogenetics refers to extensive studies of chromosomal variation and abnormalities, and their relation to disease. Cytogenetics plays an important role in identification of genetic predisposition to disease and also a person’s reaction to a certain drug.  Simpler cytogenetic technologies, such as Capillary Electrophoresis (CE), first generation amplification, and PCR (Polymerase Chain Reaction) have given way to advancements such as Fluorescence in Situ Hybridization (FISH) as well as array-based technologies, in particular array-based Comparative Genome Hybridization (aCGH). Advanced molecular cytogenetic technologies have assumed an extremely significant role in medical research. aCGH as a high-resolution tool that offers the unique ability of performing thousands of experiments in one array is fast replacing FISH technology, with advantages in terms of rapid and accurate diagnosis.

Cytogenetic techniques aid pathologists in diagnosis and prognosis related to solid tumors and hematological malignancies. With the increasing incidence of cancer worldwide, the scope of molecular cytogenetics is increasing. Better understanding of the relation between certain chromosomal anomalies and cancers has necessitated their detection through multiplex or multicolor Fluorescence In Situ Hybridization (multiplex FISH). Whole-genome tools, such as microarrays and next-generation sequencing (NGS), enable the study of the whole genome from a few malignant cells, at a resolution and precision high enough to detect abnormalities and consider potential rearrangements. Apart from improving quality of care and treatment, molecular cytogenetics also assist physicians in developing personalized therapies by leveraging the concepts of pharmacogenomics and pharmacogenetics. Demand for higher-resolution chromosomal analysis stands to benefit from research studies linking chromosomal abnormality to autism, schizophrenia, as well as cancer.

As stated by the new market research report on Molecular Cytogenetics, the United States represents the largest market worldwide. Asia-Pacific ranks as the fastest growing market with a CAGR of 27.4% over the analysis period. The growth in the region is led by growing population, high disease prevalence, unmet needs in effective disease diagnosis, rise in chromosome abnormalities due to unchecked and uncontrolled pollution in emerging economies, and growing per capita healthcare spending in developing countries like China and India.   

Major players in the market include Abbott Molecular, Agilent Technologies Inc., Applied Spectral Imaging, Biological Industries, Bio-Rad Laboratories Inc., Cytognomix Inc., CytoTest Inc., F. Hoffmann-La Roche Ltd., Illumina Inc., Leica Biosystems Nussloch GmbH, Oxford Gene Technology, PerkinElmer Inc., SciGene Corporation, and Thermo Fisher Scientific Inc., among others.

The research report titled "Molecular Cytogenetics – Market Analysis, Trends, and Forecasts" announced by Global Industry Analysts Inc., provides a comprehensive review of market trends, growth drivers, mergers and acquisitions, and other strategic industry activities of major companies worldwide. The report provides market estimates and projections for geographic markets, such as the US, Canada, Japan, Europe (France, Germany, Italy, UK, Spain, Russia, and Rest of Europe), Asia-Pacific (China and Rest of Asia-Pacific) and Rest of World. Technology segments analyzed for the market include FISH (Fluorescent In Situ Hybridization) and Array-based Technologies.  

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