The global Continuous Renal Replacement Therapy (CRRT) market is projected to reach US$1.5 billion by 2025, driven by the growing incidence of acute kidney injury (AKI) and the resulting rise in hemodynamically unstable patients. Few of the factors leading to AKI include sudden blockage of urine due to enlarged prostrate or kidney stones; kidney toxicity caused by medications; autoimmune kidney diseases such as acute nephritic syndrome and interstitial nephritis; and accidental trauma or injury to the kidneys. The aging population and the increase in the number of hospitalized elderly are also pushing up the incidence of AKI. This is because older patients in ICU with high blood pressure, chronic liver or heart diseases are at a high risk of having AKI. Benefits of CRRT driving its acceptance as a standard practice for hemodynamically unstable ICU patients include the continuousness of the therapy is physiologically similar to a normal kidney and is therefore safe and effective; higher haemodynamic stability; eliminates changes in fluid balance associated with traditional dialysis; decreased risk of long-term renal injury; patients on CRRT have over 80% reduced risk of developing chronic "end stage" renal failure; better organ perfusion; and reduced risk of developing cardiac complications as a result of sudden removal of a large amount of fluids as is the case with intermittent dialysis; and better fluid balance and electrolyte concentration.  Read More…

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