The Global Market for Huntington’s Disease Therapeutics is Projected to Exceed US$1.3 Billion by 2020
Growing Awareness Over Genetic Neurodegenerative Disorders Drives the Huntington’s
Disease Therapeutics Market, According to a New Report by Global
Industry Analysts, Inc.
GIA announces
the release of a comprehensive global report on Huntington’s Disease
Therapeutics. The
global market for Huntington’s Disease Therapeutics is projected to exceed US$1.3
billion by 2020, driven by growing awareness about the disease worldwide and
the huge unmet patient needs.
Huntington’s Disease (HD) is
a genetic, progressive neurodegenerative brain disorder caused by mutation in
the gene coding for ‘Huntingtin’ protein. Current HD therapeutics is limited to symptomatic treatments and there
are no treatment options with proven safety and efficacy to slow down disease
progression or enhance survival rate. Due to lack of approved medications, the clinical needs of HD
therapeutics are largely met with off-label use of conventional anti-epileptics
and anti-psychotic drugs. Off-label use of these medications is widespread due
to the lack of approved alternatives. Growth in the market is driven by rising prevalence
of and awareness about the disease, unmet patient needs, and ongoing research on
Huntington's disease.
Growth in global
market value is forecast to benefit from the high cost of the only approved
therapy, Xenazine®. Xenazine® represents the only FDA approved drug in the
United States indicated for HD and prescribed for the treatment of chorea
associated with the disease. The 'orphan drug’ status of Xenazine® makes the
drug expensive. The drug’s generic version, Tetrabenazine has been in use for over
three decades in many countries throughout Europe. Successful launch of late
stage drugs currently in pipeline has the potential to offer stiff competition
to Xenazine® in the future. SD-809 by Auspex Biopharmaceuticals, PBT2 by Prana,
RP103 by Raptor, and Teva Pharmaceutical’s Huntexil® represent popular pipeline
drugs for HD.
As stated
by the new market research report on Huntington’s
Disease Therapeutics, the United States represents the largest and the
fastest growing market worldwide with a CAGR of 21.6% over the analysis period.
In the United States, Huntington’s Disease
Parity Act of 2013 successfully waived off the earlier 2-year waiting period
for HD patients for gaining eligibility for disability assistance through
Medicare and Medicaid.
Major players in the marketplace include Alnylam
Pharmaceuticals Inc., Auspex Pharmaceuticals, Inc., Intellect Neurosciences
Incorporation, Lundbeck A/S, Prana Biotechnology Limited, Raptor Pharmaceuticals
Corp, Sangamo Biosciences, Inc., Teva Pharmaceutical Industries Ltd., Trophos
SA, Valeant Pharmaceuticals International, Inc., and Vertex Pharmaceuticals
Incorporated.
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